Drug-free, on-the-go therapy for improved breathing and pain relief

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Drug-Free

therapy for congestion and pain relief which can be used alone or in combination with all other existing treatments

Non-Invasive

device automatically activated by skin contact, stimulates internal tissue using precisely modulated acoustic waves

Easy to use

simple and hand-held; our device can be used anywhere, by anyone, as often as needed, with a two minute treatment

Targeted,
rapid relief.

Chronic nasal congestion, a symptom of chronic rhinosinusitis and rhinitis, affects 1 in every 5 people, causing them to experience constant discomfort, pain and fatigue. Current treatments are associated with limited efficacy and safety concerns.

The globally patented* and design-protected BES-1001 device is the first drug-free, non-invasive and connected treatment that provides targeted, rapid relief from nasal congestion and related pain.

Currently in clinical development, BES-1001 is expected to be registered by early 2024.

*Patents: WO2020/245467 and WO2020/245466

How it works

BES-1001 delivers precisely-modulated acoustic energy (PMAE) that gently travels through the tissue to relieve sinus and nasal congestion, pressure and pain.   

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Applied against the cheekbone

BES-1001 activates upon contact with the skin and produces PMAE that travels into the nasal cavity and sinuses, lasting 1 minute per cheeckbone

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Tissue oscillation

PMAE excites the resonant frequency of the sinuses, stimulates nitric oxide release and promotes clearance of the nasal passages.

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Inhibiting pain signalling

Acoustic energy activates mechanoreceptors, ‘closing the gate’ to pain fibre signals and inhibiting their transmission to the brain.

Clinical validation of mechanism of action

oscillation of
congested sinuses

76%

faster mucociliary
clearance

2x

better sinus
ventilation

What users are saying about BES-1001

“I have been sleeping for the last 20 years with a CPAP machine, and in case of a cold or infection in my nose, I cannot use the CPAP. I have been using the BES-1001 consistently for 2 years, early in the morning and late at night and during these years I was not affected by any nose infections or cold so I was able to use the CPAP. Now, I always ensure that I carry the BES-1001 with me on all my travels, giving me the confidence and relief of breathing correctly.”

Male volunteer user; sleep apnoea patient who uses Continuous Positive Airway Pressure (CPAP) machine

“When I have a cold, I manage to treat it successfully with the BES-1001. The BES-1001 has become a family device.”

Female volunteer user; patient with common cold and nasal congestion symptoms

“The device was very easy to use and comfortable during treatment. I felt immediately decongested and could breathe better!”

Male volunteer user with nasal congestion

“I am happy to say that using the above device helped me to give up the cortisone nasal spray, and in a very short time”

Female volunteer user with chronic rhinosinusitis patient and allergies

“For me it is very important the device I feel really better!”

Male volunteer user with chronic rhinosinusitis
BioEleSonic
a game-changing medical device company

We are a Swiss medical device company that develops drug-free, non-invasive medical devices for the treatment of high-prevalence chronic nasal and pain conditions. Leveraging our network of international partners, we are committed to developing medical devices that harness the power of PMAE therapy and continue to research its applications in further indications.


We aim to reshape treatment paradigms with ground-breaking therapies that are effective, safe and that meaningfully address patient convenience.

Latest News

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November 30, 2022

BioEleSonic attends the Biotechgate Digital Partnering Event | 28 November - 2 December 2022

Swiss Biotech Day

May 2, 2022

SynDermix attends SWISS BIOTECH DAY 2021 proudly presenting BES-1001 | 2 May 2022

8th China Healthcare summit

November 19, 2021

BioEleSonic virtually attends the 8th China Healthcare Summit
| 16-19 November 2021

Medica

November 15, 2021

BioEleSonic attends MEDICA Trade fair 2021 with a stand presenting BES-1001 | 15-18 November 2021